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This includes the proliferation and expansion of T cells at the ocular surface, causing damage, reactivation of acute pro-inflammatory innate responses, and, as immune regulation is lost, a vicious cycle of pathological immune reactions [106, 107]

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Elvira-Torales L

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Although the change from eumelanin (dark pigment) to pheomelanin (lighter pigment) is more closely associated with internal glutathione, topical glutathione nevertheless supports lighter pigment pathways by reducing oxidative triggers and improving cellular repair

1-3 Domestication has had a profound impact on the biology of mans best friend, shaping its genetics, physiology, and behavior to adapt it to coexistence with humans